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iMRT
HBV-M: S117F
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HBV mutation literature information.
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1
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance.
PMID:
26322642
2015
PloS one
Discussion:
The compensatory mutations discovered thus far in the
YMDD
mutants include
rt
L180M
,
L80I/V
,
V173L
,
S117F
, and
L229F/V
.
2
Identification of hepatitis B virus
rt
S117F
substitution as a compensatory mutation for
rt
M204I
during lamivudine therapy.
PMID:
22001270
2012
The Journal of antimicrobial chemotherapy
Abstract:
Additionally, virion and hepatitis B
surface
antigen secretion of the
rt
S117F
mutant was significantly impaired.
Abstract:
CONCLUSIONS: The
rt
S117F
substitution served as a compensatory mutation for
rt
M204I
.
Abstract:
Emergence of the
rt
S117F
mutation in lamivudine-resistant patients carrying
rt
M204I
was associated with increased
hepatitis
activities.
Abstract:
Emergence of the
rt
S117F
mutation was associated with an increase in
hep
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Co-occurred Entities
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2015
2012
Abstract
Discussion
26322642
22001270
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