Abstract: In addition, when pUC1.2x and pUC1.2x/
S106A were transfected, mutant virus titre was decreased 2.31-fold compared with WT virus titre.
Abstract: In vitro phosphorylation with
core mutants (
S26A,
T70A,
S106A and
T114A) revealed that the Ser(106) mutation inhibited phosphorylation of
core by PKC.
Abstract: When either pCMV/FLAG-
Cp149[WT (wild-type)] or pCMV/FLAG-
S106A Cp149 was transfected into Huh7 human
hepatoma cells, mutant
capsid level was decreased by 2.06-fold with the
S106A mutant when c