Introduction: In the following years, other mutations observed on the a-determinant, which are considered as immune escape variants, including T116N, P120S/E, I/T126A/N/I/S, Q129H/R, M133L, K141E, P142S, and D144A/E, have also been reported.
Characterization of Antigen Escape Mutations in Chronic HBV-Infected Patients in Upper Egypt.
8Discussion: Several other studies reported other substitutions in the ""a"" determinant region and associated with vaccine escape, such as T116N, P120S/E, I/T126A/N/I/S, Q129H/R, M133L, K141E, and D144A/E."
HBV genotypes and drug resistance mutations in antiretroviral treatment-naive and treatment-experienced HBV-HIV-coinfected patients.
Method: The sequences were examined for known vaccine escape mutations (sG145R/A, sP142S, sI/T126A/N/I/S, sQ129H/R, sM133L, sD144A/E, sP120S/E, sK141E, sP134I, and sT116N), immunoprophylaxis escape mutations (
Molecular characterization of hepatitis B virus in Vietnam.
1Abstract: RESULTS: Ten HBsAg mutants having single mutation within the ""a"" determinant including P120E, T123N, Q129H, M133L, K141E, P142S, D144A, G145R, N146S and C147S together with a wt form were successfully constructed and expressed in CHO cells."
HBV mutation literature information.
PMID: 
2021
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