Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression.
PMID: 29713126
2018
World journal of gastroenterology
4Method: Of six positions' mutation in the A-B interdomain, three RT mutations, rtD134E/N, rt Method: Of note, the following four putative or pretreatment mutations found in treatment naive patients, rtD134E/N, rtN139D/E/H/K/Q, rtF221Y, and rtI224V, are also reported as associated with progression of severe liver diseases, such as HCC and cirrhosis (described below).
Characterization of antiviral resistance mutations among the Eastern Indian Hepatitis B virus infected population.
HBV mutation literature information.
PMID: 
2018
World journal of gastroenterology
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