Pre-S/Surface and Core Promoter/Precore Mutations in Chronic Hepatitis B Patients with Severe Acute Exacerbation.
PMID: 30835025
2019
Digestive diseases and sciences
Abstract: Multivariate analysis showed that the independent factors for SAE were V14G/A and L21S in surface genes, codons 109-119 deletions in pre-S1 genes, M1V/T/I in pre-S2 genes, and C1766T/T1768A and C1913A/G mutations in BCP/PC genes.
Comparison of pre-S1/S2 variations of hepatitis B virus between asymptomatic carriers and cirrhotic/hepatocellular carcinoma-affected individuals.
PMID: 31501793
2019
Clinical and experimental hepatology
Result: From them, L11Q, N37S and K38R were more prevalent, but L19* (stop codon), M1T, T5P/A, G29A and N32D were also observed with lower prevalence.
Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala, India.
PMID: 24409056
2013
World journal of gastroenterology
Abstract: The preS2 start codon M1T/I mutation was unique to genotype A strains (15.6%) from all disease groups and occurred at a higher frequency in isolates from HCC patients (P = 0.076).