Abstract: Furthermore, reactivated HBV in 11 of 16 (69%) non-HSCT cases possessed substitutions associated with impaired virion secretion, including E2G, L77R, L98V, T118K, and Q129H in the S region, and M1I/V in the PreS2 region.
Result: Amino acid substitutions of sE2G (n = 3), sL77R (n = 1), and sL98V (n = 1) in the small S protein that were associated with impaired virion secretion were also the pr
Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.
Abstract: Four sites (A5T/S, L21S, T/A126S and T/N131I/A) and 13 sites (N3S, T5A, G10Q/R/E, L21S, T47K/A/V, L98V/P, I/S126N/V/T, Q129H/R/L, T131P/I/N/A, G145A/R, L175S/F, L213I/S, V224A/G) were found to be under positive selection in genotype B and C HBV vaccine escape strains, re
Characterization of the occult hepatitis B virus variants circulating among the blood donors from eastern India.
Result: At least 4 different genotype/subgenotype unrelated aa mutations are observed: V96A (1/47; 2.13%), L98V (1/47; 2.13%), Y100C (1/47; 2.13%), and I1110L (3/47; 6.38%) (data not shown).
Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
PMID: 20119580
2010
Journal of Korean medical science
Result: Similarly, in Group P, there was one case of each of the following mutations: F41C, A45V, P49L, Q54L, P62L, I92T, L98V, T140S, A157V, W182stop, and S204R.
Comparison of the technical and clinical performance of the Elecsys HBsAg II assay with the Architect, AxSym, and Advia Centaur HBsAg screening assays.
Abstract: However, the Elecsys HBsAg II assay recognized a native mutant sample (L94S, L97V, L98V, T123A) that the Architect HBsAg assay failed to detect.
HBV mutation literature information.
PMID: 
2022
PloS one
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