rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome.
Result: Of the four rt269I signature types, I84T/M/L/V in PreS1 has been reported to be frequently found in HBV occult cases.
Result: We found a total of five types of signature NS mutations in the S ORF (I84T/M/L/V and A90T/V in PreS1, F141L in PreS2, and I68T and L213I/S in S).
Table: I84T/M/L/V
Discussion: Indeed, we found several rt269I signature mutation types related to lower HBV replication ( PMID: 29434654
2018
Infectious agents and cancer
Result: The different mutations detected were W4R, S5A/P/T, L30S, G35R, H51P/R, E54K, A60V, W77R/Stop, I84T, N98 K/T, G102R, Q118R/Stop, N123D and S124F/P.
Table: I84T
[Analysis of hepatitis B virus (HBV) preS1, preS2 and S gene regions from patient groups infected with HBV genotype D].
Result: Besides I84T found in C1, no mutations of occult HBV infection were detected.
Result: Five mutations from the control group were found at the same location (aa58-aa100), including A60V in nine patients (C2, C3, C12, C13, and C16-C20), L74I in C2, I84T in C1, L85V in C2, and A95V in C3.
Discussion: In the same study, S17A, P32L, W43L/R, H51P/R, and I84T/M of the pre-S1 region and W3R/Stop and S5A of the pre-S2 region were foun
Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
PMID: 20119580
2010
Journal of Korean medical science
Result: Three cases of I84T mutations were found in Group C, compared to only one in Group P.
HBV mutation literature information.
PMID: 
2021
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