literature

HBV mutation literature information.

COLD-PCR Method for Early Detection of Antiviral Drug-Resistance Mutations in Treatment-Naive Children with Chronic Hepatitis B.

PMID: 32708399 2020 Diagnostics (Basel, Switzerland)

Result: Among these above 94 cases, there were 11 cases carrying additional mt that are not related to drug resistance, such as rtI187V (+ rtV207M) x 2 cases, rtI187V (+ rtS213T), rtI187V (+ rtP237T), rtI187V (+ rtL229V), rtI187V (+ rtV207M + rt

Discovery of the Novel Entecavir-Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis.

PMID: 30202825 2018 Hepatology communications

Table: I187V

Impact of the rtI187V polymerase substitution of hepatitis B virus on viral replication and antiviral drug susceptibility.

PMID: 25028473 2014 The Journal of general virology

Abstract: A high prevalence of the rtI187V polymerase substitution of hepatitis B virus (HBV) was detected in nucleoside/nucleotide-analogue-naive and -treated chronic hepatitis B (CHB) patients.

Abstract: Furthermore, rtI187V HBV remained susceptible towards treatment with LAM or ADV in vitro whereas the combination of the rtI187V substitution with LAM-resistant mutations rendered HBV resistant to LAM but still sensitive to ADV.

Abstract: However, the emergence of the rtI187V substitution significantly impaired viral replication but without affecting drug sens

Occult hepatitis B virus infection among blood donors in Colombia.

PMID: 25471066 2014 Virology journal

Abstract: The mutations rtL108P, rtR110G, rtR192C, rtT150S and rtI187V were characterized for the first time in these samples.

Conclusion: Additionally, three nonsynonymous mutations were found in the ORF S, S region,

Result: Additionally, rtR192C, rtI187V and rtT150S substitutions were observed in samples 024, 038 and 123, respectively (Figure 4).

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