Result: In patient n 6 no mutation was observed in the pre-S1, pre-S2 and S regions in the HCC tissue, whereas in the non-HCC liver tissue the N59T and I110L AA substitutions were observed in the S region, no mutation in the pre-S1 region and the AA substitutions H114T and I165L in the pre-S2 region.

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Result: The following AA substitutions and deletions were observed: a) G44E, I92T, Q129H,