HBV mutation literature information.


  Identification and Characterization of Besifovir-Resistant Hepatitis B Virus Isolated from a Chronic Hepatitis B Patient.
 PMID: 35203489       2022       Biomedicines
Abstract: The ten mutations include rtV23I (I), rtH55R (R), rtY124H (H), rtD134E (E), rtN139K (K), rtL180M (M), rtM204V (V), rtQ267L (L), rtL269I (I) and rtL336M (M).
Result: When compared to the WT, Clone 1-1 harbored 10 mutations (IRHEKMVLIM: rt


  Impacts of HBV rtH55R polymerase substitution on viral replication and rtM204I/V resistance to nucleoside/nucleotide antiviral drugs.
 PMID: 28440785       2018       Antiviral therapy
Abstract: CONCLUSIONS: We identified a new HBV RT substitution of rtH55R in genotype-C-infected CHB patients.
Abstract: In vitro studies showed that rtH55R had a similar HBV DNA level compared to wild type.
Abstract: The rtH55R+rtM204I


  Occult HBV Infection May Be Transmitted through Close Contact and Manifest as an Overt Infection.
 PMID: 26457811       2015       PloS one
Result: Amino acid substitutions in mother include T16I, R41S, V44A,N53S, H55R, W58R, N76D, S81T, V103I, G107E, N121I, I122L, N123D, Q125K, H126Y, N134D, N139H, N139Q, Y158H, I163V, F178L, S185N, V207M


  Amino acid similarities and divergences in the small surface proteins of genotype C hepatitis B viruses between nucleos(t)ide analogue-naive and lamivudine-treated patients with chronic hepatitis B.
 PMID: 24316031       2014       Antiviral research
Abstract: With little influence on immune escape-associated mutation frequencies within 'a' determinant, LMV-monotherapy significantly induced classical LMVr-associated mirror changes sE164D/rtV173L, sI195M/rtM204V and sW196L/S/rtM204I, as well as non-classical ones sG44E/rtS53N, sT47K/A/rt



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