Abstract: CONCLUSIONS: We identified a new HBV RT substitution of rtH55R in genotype-C-infected CHB patients.
Abstract: In vitro studies showed that rtH55R had a similar HBV DNA level compared to wild type.
Abstract: The rtH55R+rtM204I
Abstract: The replication capacity of the rtM204I clone was found to significantly decrease under lamivudine treatment, but this was not found in the rtH55R+rtM204I clone.
Occult HBV Infection May Be Transmitted through Close Contact and Manifest as an Overt Infection.
Amino acid similarities and divergences in the small surface proteins of genotype C hepatitis B viruses between nucleos(t)ide analogue-naive and lamivudine-treated patients with chronic hepatitis B.
Abstract: With little influence on immune escape-associated mutation frequencies within 'a' determinant, LMV-monotherapy significantly induced classical LMVr-associated mirror changes sE164D/rtV173L, sI195M/rtM204V and sW196L/S/rtM204I, as well as non-classical ones sG44E/rtS53N, sT47K/A/rt