Result: The point-mutations on the S gene that owned the rates of >30% of the population were: S53L (37.7%), A184V/G (39.3%), and S210K/N/R/S (39.3%); from 15 to <30% were L21S (29.1%), G44E/V (18.6%), I126T/N/S (21.1%), and M198I/M (18.2%); and from 5 to <15% were V14A/G/Q (10.1%), N40S/K (6.9%), T47A/E/V/K (9.3%), P/L49R/H (5.7%), P62Q/L (9.7%), C76Y/T/W (10.5%), Y100C/F
Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission.
Conclusion: G44E, G102C, and Y161F were detected in the serum of the 1st-born, the umbilical cord of the 1st-born, and the umbilical cord of the 3rd-born child, respectively.
Conclusion: G44E, P56L, F93S, C107Y, L110P, S117 N, T118K, D144A and W167 L were detected in only one sample.
Table: G44E
Small surface antigen variants of HBV associated with responses to telbivudine treatment in chronic hepatitis B patients.
Abstract: CONCLUSIONS: Our findings suggest that the decrease in viral population heterogeneity at an early stage of LdT treatment was associated with the subsequent optimal virological response, and the early appearance of some specific mutations, such as sG44E, sW172* and sW182*, is a potential indicator of a partial virological response in continuing therapy.
Abstract: RESULTS: Sequencing results revealed different dynamics of non-synonymous mutations, such as sL9P, sN40S, sG44E, sW172*, PMID: 27486882
2016
Oncotarget
Result: In this patient, the HCC tissue showed no mutation in the S region, AA substitutions L54P and G76A and AA deletions in positions 4, 8 and 17 in the pre-S1 region and AA substitution P41H in the pre-S2 region, whereas the non-HCC liver tissue showed the G44G/E and I92T AA substitutions in the S region, G91A and I255T AA substitutions in the pre-S1 region and AA substitutions G99E and I147T
Amino acid similarities and divergences in the small surface proteins of genotype C hepatitis B viruses between nucleos(t)ide analogue-naive and lamivudine-treated patients with chronic hepatitis B.
Abstract: With little influence on immune escape-associated mutation frequencies within 'a' determinant, LMV-monotherapy significantly induced classical LMVr-associated mirror changes sE164D/rtV173L, sI195M/rtM204V and sW196L/S/rtM204I, as well as non-classical ones sG44E/rtS53N, sT47K/A/rt
A multicentre molecular analysis of hepatitis B and blood-borne virus coinfections in Viet Nam.
HBV mutation literature information.
PMID: 
2022
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