HBV mutation literature information.


  [Monitoring by high-sensitivity HBV DNA assay during treatment in chronic hepatitis B e antigen negative patients].
 PMID: 29804376       2018       Zhonghua gan zang bing za zhi
Abstract: New mutation sites such as G1915A / C, L180M, M204V, V207I / L, T184A and V173L were detected, Low resistance rate (25%).


  Hepatitis B virus mutations, expression quantitative trait loci for PTPN12, and their interactions in hepatocellular carcinoma.
 PMID: 27075395       2016       Cancer medicine
Result: Of those 19 hotspot mutations, C1653T, T1674C/G, A1703G, G1719T, T1727A/G, T1753C, A1762T, G1764A, G1799C, G1899A, G1915A/C, and C1969T were significantly associated with an increased risk of HCC, whereas C1673T, A1726C, C1730G, and A1752G were significantly associated with a reduced risk of  PMID: 26568165       2015       Scientific reports
Method: A risk prediction model to classify the HCC cases and controls was constructed according to the following steps: (1) Prediction factor selection: HBV genotype, the 11 independent HCC-related mutations (C1653T, C1673T, T1674C/G, C1730G, A1752G, T1753C, A1762T, G1764A, G1899A, G1915A/C and C1969T), the HLA SNPs (rs9272105 and rs9275319), the HCC-related multiplicative interactions (rs9272105 with the HBV genotype,



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