Result: Only
F141V/L/I was found with a significantly higher rate in the
HCC group (18.4% vs 9.6%, p = 0.08).
Result: The point-mutations with the rates of over 30% were
T125S/N/P (30.8%),
I150T (42.5%), and
V158A (36%); from 10 to <30% of population were
M120V/I (11.3%) and
F141V/L/I (11.3%); and from 5 to <10% of population were
Q121R/K (5.3%),
T164I/D/S (6.1%), and
F165S/L (5.7%).
Discussion: Only
F141V/L/I had the higher distribution in the
HCC