HBV mutation literature information.


  Prevalence and significance of Hepatitis B reverse transcriptase mutants in different disease stages of untreated patients.
 PMID: 22882650       2012       Liver international
Abstract: rtS106C, rtD134E/G/N/S and A-B interdomain mutations may be associated with necro-inflammation, immune response and cirrhosis development at ages older than 40.
Abstract: And the rtD134E/G/N/S mutations were also higher in chronic hepatitis B patients (22/100, 22.0%) and cirrhotic patients (21/100, 21.0%) than that in hepatocellular carcinoma patients (10/100, 10.0%, P = 0.021 and P = 0.032 respectively).
Result: Additionally, A significant portion of patients with



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