Hepatitis B virus precore/core region mutations and genotypes among hepatitis B virus chronic carriers in South-Eastern, Nigeria.
PMID: 33708042
2021
International journal of health sciences
Discussion: Furthermore, the core gene mutations previously reported to be associated with liver disease progression in chronic patients and particularly in HCC patients such as C1913A/G, C1914G, and G1915T were not identified in any of the sequences from this study.
Hepatitis B virus gene mutations in liver diseases: a report from New Delhi.
Abstract: C1914G core gene mutation was associated with the hepatocellular carcinoma (32.2%) compared to other groups.
Abstract: CONCLUSION: Mutations such as T1762/A1764, T1753V and C1914G were usually associated with advanced forms of liver disease and had an increased risk of HCC.
Result
Result: Further, the C1914G core gene mutation was associated with the HCC cases (32.2%) compared to ASC (5.0%), CHB (7.8%) and LC (10.3%), respectively.