Result: The Kozak sequence mutants (nt 1809-1812) with a prevalence of 51.7% (74) includes T1809G (32.9%), C1810A/T (2.8%), A1811C (9.8%) and T1812C (38.5%) (Table 2).
Figure: *The translational or the Kozak sequence mutants include T1809G, C1810A/T, A1811C and T1812C.
Hepatitis B virus subgenotype C2- and B2-associated mutation patterns may be responsible for liver cirrhosis and hepatocellular carcinoma, respectively.
PMID: 23903686
2013
Brazilian journal of medical and biological research
Abstract: Four patterns (C1810T, A1846T, G1862T, and G1896A) were significantly associated with HCC compared with LC.
Abstract: Multivariate regression analyses showed that HBV subgenotype C2 and C2-associated mutation patterns (C1653T, T1753C, A1762T, and G1764A) were independent risk factors for LC when CHB was the control, and that B2-associated mutation patterns (C1810T, A1846T, G1862T,
HBV mutation literature information.
PMID: 
2018
PloS one
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