literature

HBV mutation literature information.

Investigation of DNA sequence in the Basal core promoter, precore, and core regions of hepatitis B virus from Tunisia shows a shift in genotype prevalence.

PMID: 23346148 2012 Hepatitis monthly

Result: All observed strains who carried mutations at nt 1726 (C to A), nt 1727 (T to A or G) and nt 1730 (G to C) in EnhII region, had BCP mutation at position 1802C-1803G.

Result: The samples of 39 patients containing wild-type strain at position 1721, had G1719T, C1726A, T1727A and G1730C mutations.

Result: The wild-type strain for nt 1703 present in 18 samples, had the wild-type at the positions 1701, 1702, 1721, 1728 and 1740, but had mutant-type at nt 1719 (G to T), nt 1726 (C to A), nt 1727 (T to A) and nt 1730

Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis.

PMID: 19574418 2009 Journal of the National Cancer Institute

Table: C1726A

Discussion: Other mutations that have been shown to be statistically significantly associated with the risk of HCC, such as those at T31C, T53C, G1613A, A1703G, G1719T, C1726A, and G1730C, were not included because few patients had these mutations.

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