Abstract: Conclusions: According to the results, point mutations such as
L11Q,
N37S,
K38R and
A49V, as well as certain deletions, may be associated with
HBV infection outcome, among an HBV genotype D pure population.
Abstract: The rate of critical point mutations, including
L11Q,
N37S and
K38R, was significantly higher in the ASC group, whereas the
A49V substitution rate was significantly higher in the
LC/
HCC group (p < 0.05).
Result: By contrast, the
A49V point mutation at the transactivation domain was detected significantl