literature

HBV mutation literature information.

Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors.

PMID: 30943997 2019 Virology journal

Result: PreS2 (aa 1-55) substitutions were: V32 L, N33S, A35V, N37 T, A47S, T49I, V53A, T54P.

Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients.

PMID: 29285238 2017 Oncotarget

Result: Univariate analysis showed that age (p < 0.0001), HBV viral load (p < 0.0001), mutation from A to S at aa47 (p = 0.047), mutation from H to Y at aa94 (p = 0.002), mutation from I to T at aa127 (p = 0.001), mutation from F to Y at aa132 (p = 0.001) and mutation from A to V at aa146 (p = 0.025) showed a significant correlation with HBV-related LC+HCC (Table 5).

Table: A47S

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