HBV mutation literature information.


  Pro-oncogenic, intra host viral quasispecies in Diffuse large B cell lymphoma patients with occult Hepatitis B Virus infection.
 PMID: 31601912       2019       Scientific reports
Table: Ala36Thr


  Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations.
 PMID: 19327810       2009       Virology
Discussion: Moreover, together with the results of chimeric constructs they suggest that mutations present at the N-terminus of 2A core protein (A36T or G63V) reduce the stringency of virion secretion, whereas mutations present at the C-terminus of the 4B core protein (T147A, R151C, D153G, or Q179K) enhance genome maturity of secreted virions.


  A study on sequence variations in pre-S/surface, X and enhancer II/core promoter/precore regions of occult hepatitis B virus in non-B, non-C hepatocellular carcinoma patients in Taiwan.
 PMID: 19431214       2009       International journal of cancer
Abstract: Compared with the HBsAg-positive HCC controls, occult HBV-infected HCC patients had higher frequencies of M1I and Q2K in pre-S2 gene, G185R and S210N in surface gene, A36T and A44L in X gene, and G1721A in enhancer II gene, and had lower rates of pre-S deletions and A1762T/G1764A,



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