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 HBV mutation literature information.


  Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.
 PMID: 35390033       2022       PloS one
Table: A159V


  Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.
 PMID: 32994690       2020       World journal of gastroenterology
Abstract: HBsAg production was significantly lower and the replication capacity was significantly higher, without a significant difference in LAM/ETV susceptibility, in sA159V-containing LAM/ETV-resistant mutants than in their sA159V-lacking counterparts.
Abstract: Among these, sA159V was detected in 1.95% (136/6982) of patients with resistance mutations and 1.08% (134/12,458) of patients lacking resistance mutations (P < 0.05).
Abstract: Phenotypic analyses were performed to evaluate HBsAg production, replication capacity, and drug-induced viral inhibition of patient-derived drug-resistant mutants with or without the coexistence of sA159V


  Molecular and serological characterization of occult hepatitis B among blood donors in Maputo, Mozambique.
 PMID: 32997000       2020       Memorias do Instituto Oswaldo Cruz
Table: A159V


  Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China.
 PMID: 31269905       2019       BMC infectious diseases
Table: A159V/G


  Serological Patterns and Molecular Characterization of Occult Hepatitis B Virus Infection among Blood Donors.
 PMID: 27882070       2016       Hepatitis monthly
Abstract: Mutations in the S region of HBV DNA included S114T, G119R, P120S, T125M, C139Y, T140I, C147W, T148A, A159V/G, E164D, V168A, and R169C.
Result: Variants were found in 30.4% (21/69) of cases with OBI and included S114T, G119R, P120S, T125M, C139Y, T140I,


  Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.
 PMID: 22500577       2012       Virology journal
Result: D99N, Q101R/H, L109I, I110N, T115S, S117T, P120S, K122R, S126T/A, P127H, A128V, Q129R/H/L, G130E, T131N/A, M133T/L/S, F134R/I/L, T143M, A159V, F161Y, W163G, E164G, V168A


  "Identification of hepatitis B surface antigen variants with alterations outside the ""a"" determinant in immunized Singapore infants."
 PMID: 9841851       1999       The Journal of infectious diseases
1Abstract: Decreased binding to ""a"" determinant-specific monoclonal antibody was observed for variants Pro120 to Ser120, Ala159 to Val159, and Phe183 to Cys183."
Abstract: These include Asn116 to Thr116, Val118 to Ala118, Pro120 to Ser120, Ala159 to Val159, Phe183 to Cys183, and Val184 to Ala184.



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