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 HBV mutation literature information.


  Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.
 PMID: 35390033       2022       PloS one
Table: A128V


  Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations.
 PMID: 33893696       2021       Journal of viral hepatitis
Result: T118A/R/V, A128V and S/T143L/M had the highest prevalence in genotype D and in Europe, being present >3% of the sequences.
Result: Other VEMs that had an overall prevalence of >1% were T118A/R/V, M133I/L/T, A128V, Q129H/N/R, G145A/R, P120S/T and S/T143L/M (Figure 2A).
Discussion: For example, T118A/R/V, A128V and D144A/E/G/N variants are more common in Europe, which may relate to better vaccine c


  Detection of circulating hepatitis B virus immune escape and polymerase mutants among HBV-positive patients attending Institut Pasteur de Bangui, Central African Republic.
 PMID: 31682960       2020       International journal of infectious diseases
Abstract: Potential IEMs sY100C, sA128V, and sM133T, and several polymerase mutants were identified.
Result: Six of these (sL127I, sA128V, sG130S, sM133T, sF134I, and S140T) were located in the 'a' determinant region, among which three immune escape mutants (IEMs) (sY100C


  Case Report: Application of hepatitis B virus (HBV) deep sequencing to distinguish between acute and chronic infection.
 PMID: 33458253       2020       Wellcome open research
Table: A128V


  Evaluation of the pol/S Gene Overlapping Mutations in Chronic Hepatitis B Patients in Northern Cyprus.
 PMID: 31880877       2019       Polish journal of microbiology
Result: The mutation patterns were sI110L + sS193L, sP120L + + sT123N + sT126I + sA128V + sY134H + sD144E + +sG145A, sT118A+sP127T, sI110L+


  Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence.
 PMID: 29315352       2018       PloS one
Method: In addition, we looked for Vaccine Escape Mutants (VEMs) and polymorphic mutations outside (Y100C, Q101H, S117N, T118R and P120S) and within the HBsAg immuno-dominant 'a' determinant (I/T126A/N, A128V, Q129H/R, G130N, M133L/T, K141E, S143L, D144A/H/E and G145R).


  Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
 PMID: 29408943       2018       PloS one
Table: A128V


  Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe.
 PMID: 29859062       2018       BMC infectious diseases
Method: We determined the prevalence of 29 immune-associated escape mutations (sQ101K, sT114R, sP120S/T/A, sT123A/N, sT126N/S, sP127L, sA128V, sQ129R/N, sG130N/R, sT131I, sM133I/L/T,


  Identification of a novel tri-genotypic recombinant Hepatitis B virus in Bangladesh.
 PMID: 30040979       2018       Virus research
Abstract: Additionally, the complete genome has a frameshift deletion of nine nucleotides from overlapping Surface and Polymerase genes, and a vaccine escape mutation, A128 V, in the surface protein.


  HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
 PMID: 27354181       2017       Antiviral therapy
Abstract: In particular, the 'a' determinant surface gene mutations (sT125S, sA128V, sQ129H/R, sT131I, sC137S, sT143M, sD144D/E, sG145R, sT148P) and the majority of clustered/multiple as well as drug selected immune escape HBsAg mutations were more prevalent



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