HBV mutation literature information.


  Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.
 PMID: 25333524       2014       PloS one
Result: 15% (3/20), p = 0.01)] found in HBeAg positive patients whereas A1762T/G1764A with A1053G in enhancer-I region [54% (7/13) vs.
Result: Although the prevalence of A1053G was extremely high in both LC (50%) and HCC (50%), it was only 6% in nLF and 11% in LF (p = 0.081) whereas, T1050G/A and their combination T1050G/A+A1053G showed significant escalating trend over the course of infection from nLF (18%, 0%) to HCC (54%, 32%) through LF (22%, 11%) and  PMID: 22014121       2011       BMC cancer
Table: A1053G


  Nucleotide mutations associated with hepatitis B e antigen negativity.
 PMID: 15834874       2005       Journal of medical virology
Abstract: Six mutations were found to be significantly more common in the former group than in the latter: G529A (3/4 vs. 0/5), C934A (4/4 vs. 1/5), A1053G (4/4 vs. 1/5), G1915T/A (4/4 vs. 0/5), T2005C/A (4/4 vs. 0/5), and C3026T (3/4 vs. 0/5).



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