HBV mutation literature information.


  Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome.
 PMID: 22666402       2012       PloS one
Table: V207M


  Molecular epidemical characteristics of Lamivudine resistance mutations of HBV in southern China.
 PMID: 21959623       2011       Medical science monitor
Discussion: Other mutations and mixed combinations were also observed (rtM204I+rtV207M/L, rtM204I+rtV173L, rtM204I+rtS213T, rtM204V+rtL180M+rtV173L/M, rtM204V+rtL180M+rt PMID: 20646332       2010       Virology journal
Abstract: INTERVENTIONS AND MAIN OUTCOME MEASURE(S): Before our lab was consulted, the patient was unsuccessfully treated with interferon, an obscure drug named Hepon, which should activate antiviral immune response, and Lamivudine, the latter most likely becoming ineffective due to the mergence of resistant subpopulations (rtL180 M, rtV207 M, two strains with stop codons at position rt188 and rt198, rtM204V (YVDD), rtM204K (YKDD)).
Conclusion: Especially this latter mutation rtM204K and the mutation in the direct neighbourhood of the so


  Prevalence of hepatitis B virus DNA polymerase mutations in treatment-naive patients with chronic hepatitis B.
 PMID: 19785624       2009       Alimentary pharmacology & therapeutics
Abstract: Some (16.7%) had mutations of unknown clinical significance (rtV207M/L/I) and only 4 patients had rtA181A/S, rtA194S or M250I.



Browser Board

 Co-occurred Entities




   Filtrator