HBV mutation literature information.


  Prevalence of hepatitis B virus DNA polymerase mutations in treatment-naive patients with chronic hepatitis B.
 PMID: 19785624       2009       Alimentary pharmacology & therapeutics
Abstract: Some (16.7%) had mutations of unknown clinical significance (rtV207M/L/I) and only 4 patients had rtA181A/S, rtA194S or M250I.


  [Long-term clevudine therapy in nucleos(t)ide-naive and lamivudine-experienced patients with hepatitis B virus-related chronic liver diseases].
 PMID: 19581770       2009       The Korean journal of hepatology
Abstract: Proven sites of mutation of HBV DNA polymerase in naive patients were, for example, L80I, L180M, A181V/T, M204I and V207I.


  Prevalence, incidence, and clinical relevance of the reverse transcriptase V207I mutation outside the YMDD motif of the hepatitis B virus polymerase during lamivudine therapy.
 PMID: 15872296       2005       Journal of clinical microbiology
Abstract: The reverse transcriptase V207I mutation within the hepatitis B virus (HBV) polymerase is associated with resistance to lamivudine in vitro.


  Detection of hepatitis B virus variants resistant to lamivudine and famciclovir among randomly selected chronic carriers from Spain.
 PMID: 14987532       2004       Enfermedades infecciosas y microbiologia clinica
Abstract: Wild-type strains together with either the rtM204I (M552I) or rtV207I (V555I) point mutation were found in two of these cases, and the rtV207I mutation alone was detected in the third.



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