Abstract: Most OBI strains were wild-type HBV, but some substitutions V168A, S174 N, V177A, Q129R/L/H, G145A/R in S region of genotype B (OBIB) and T47K/V/A, P49H/L, Q101R/H/K, S174 N, L175S, V177A, T118 M/R/K, G145R/A/K/E, R160K/N in S region of genotype C (OBIC) strains were identified in high frequency.
T
Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers.
PMID: 25320728
2014
Clinical and molecular hepatology
Abstract: The mutations include T123S, M125I/N, C139R, D144E, V177A, L192F, and W196L, some of which have not been reported before.
Result: Taking the entire MHR region into consideration, three additional patients contained amino acid substitutions: T123S, V177A, L192F, and W196L.
HBV mutation literature information.
PMID: 
2019
BMC infectious diseases
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