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 HBV mutation literature information.


  T3098C and T53C mutations of HBV genotype C is associated with HBV infection progress.
 PMID: 20337225       2009       Biomedical and environmental sciences
Abstract: CONCLUSION: The frequency of genotype C HBV preS T3098C and T53C mutations is associated with hepatitis B infection progression.
Abstract: RESULTS: The prevalence of preS T3098C and T53C mutations of genotype C HBV was significantly higher i
Abstract: The rate of T3098C mutation in ASC, CHB, LC, and HCC patients were 0.00% (0/24), 3.85% (1/26), 9.09% (2/22), and 30.77% (8/22), respectively (P=0.0015), while the rate of T53C mutation was 12.50% (3/24), 3.85% (1/26), 40.91% (9/22), and 42.31% (11/26), respectively (P=0.0012).


  Genotype-specific genomic markers associated with primary hepatomas, based on complete genomic sequencing of hepatitis B virus.
 PMID: 18216102       2008       Journal of virology
Abstract: HCC-related mutations T31C, T53C, and A1499G were associated with HBV subgenotype Ce, and mutations G1613A, G1899A, T2170C/G, and T2441C were associated with HBV subgenotype Cs.



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