Result: All the mutations were synonymous, except
T528C which resulted in an amino acid change (
Met125Thr) in the '
a' determinant of the
S protein.
Result: Analysis of the
S gene amplicon sequences from 10 patients identified 10 mutations - 8 mutations common to all patients (
C373T,
C493A,
C505T,
C514A,
T528C,
A616G,
T619C,
T667C), whereas 2 mutations,
T364C and
A541G were specific to patients 8 and 11 respectively.
HBV mutation literature information.
PMID: 
2019
Scientific reports
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