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 HBV mutation literature information.


  [The prevalence of hepatitis B virus precore mutant isolated from asymptomatic carriers in Guangxi].
 PMID: 12667359       2002       Zhonghua liu xing bing xue za zhi
Abstract: Both mutation at nt1856 (C-->T) and nt1858 (T-->C) could be seen in sample 734.
Abstract: The common mutation in the southern part was seen T-->C at nt1858 while nt1896 stop mutation was discovered in one sample only, which was accompanied by point mutation at nt1837 (A-->G).


  Low frequency of mutations in the core promoter and precore regions of hepatitis B virus in anti-HBe positive Brazilian carriers.
 PMID: 11472634       2001       BMC microbiology
Discussion: Changes at positions 1762-1764 have been described to be preferentially selected in patients infected with genotypes showing C instead of T at nt 1858.


  Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal.
 PMID: 8171038       1994       Proc Natl Acad Sci U S A
Abstract: The commonest conserved mutation was M0: T-->C at position 1858, Pro-->Pro at codon 15.


  Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members.
 PMID: 8188166       1994       Hepatology (Baltimore, Md.)
Abstract: M0, a conserved mutation (T-to-C at nucleotide 1858, codon 15), was detected in 81% and 12% family members of index patients with and without M0, respectively (p < 0.0001).



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