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HBV-M: T184L
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Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues.
PMID:
19302908
2009
Clinical therapeutics
Abstract:
A total of 9.1% (4/44) of the clones harbored the
rt
L180M
+
rt
T184L
+
rt
M204I
mutations.
Abstract:
At week 22 during ADV treatment, LAM-resistance mutations (
rt
L180M
,
rt
T184L
,
rt
M204I
,
rt
V191I
, and
rt
L229V
) were not detected.
Abstract:
The
rt
M204I
mutation was associated with compensatory mutations (
rt
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T184L
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Chronic Hepatitis B
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Table
35359734
34319801
34007795
33562603
33124952
32994690
32708399
32216026
31558731
31498528
31189581
31147594
31130120
31130119
30906435
30866789
30202825
30080852
28749433
26612031
26322642
25596179
25061278
24993731
24836314
24788140
23701433
23166535
22878399
22666402
22453135
21933446
21696601
21492508
21392168
20169198
19933798
19918102
19302908
19301976
19125938
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