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 HBV mutation literature information.


  The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes.
 PMID: 19041149       2009       Journal of hepatology
Abstract: rtM204V clusters with mutations localized in the RT-B domain (rtV173L, rtL180M, and rtT184A/S) (bootstrap=0.94), while rtM204I clusters with mutations localized in the RT-A domain (rtS53N, rtT54Y, and rtL80I/V) (bootstrap=0.96) (without associations with HBsAg specific mutations).


  [Entecavir resistance in entecavir naive lamivudine treated chronic hepatitis B patients].
 PMID: 19795617       2009       Mikrobiyoloji bulteni
Abstract: rtT184A, rtT1841 and rtT1845 mutations were found related to primary ETV resistance.


  Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.
 PMID: 19301976       2009       The Journal of infectious diseases
Method: Established NRTI-resistance mutations included the following RT mutations: rtL80V/I, rtI169T, rtV173L, rtL180M, rtA181TV, rtT184S/A/I/L/F/G, rtA194T, rtS202G/I, rtM204V/I/S, rtN236T, and rt



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