literature

HBV mutation literature information.

Analyses of the Genetic Diversities and Mutations of the Hepatitis B Virus Genome BCP/Pre C Region.

PMID: 30702819 2017 Bing du xue bao

Abstract: Other mutations in descending order by mutation rate were a: A1762T/G1764A combined mutation (90. 48%); G1756C/T1803A/A(1757 ~ 1765)/A (1824 ~ 1832) combined mutation (80. 95%); T1753C/A1762T/ G1764A combined mutation (57. 14%); A1762T/G1764A/G1896A combined mutation (42. 86%); G1756C/_(1757~176.5) combined mutation,(28. 57%); T1753C/A1762T/G1764A/G1896A combined mutation (23. 81%).

Prevalent HBV point mutations and mutation combinations at BCP/preC region and their association with liver disease progression.

PMID: 20846420 2010 BMC infectious diseases

Result: In univariate binary logistic regression analysis, all the top five high occurrence mutations seemed to relate to ALD, including T1753A/C (OR = 3.2, 95% CI: 1.3-7.9, P = 0.013), A1762T (OR = 3.1, 95% CI: 1.5-6.5, P = 0.003), G1764A (OR = 4.8, 95% CI: 2.1-10.9, P < 0.001), T1803A/G (OR = 5.1, 95% CI: 1-25.4, P = 0.058), and G1896A (OR = 2.4, 95% CI: 1.2-5.0, P = 0.015).

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