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 HBV mutation literature information.


  Prevalence, genotype distribution and mutations of hepatitis B virus and the associated risk factors among pregnant women residing in the northern shores of Persian Gulf, Iran.
 PMID: 35271684       2022       PloS one
Abstract: Of note, the conversion of Ala Val at amino acid 168 (A168V) and Thr Pro at amino acid 127 (T127P) were detected in HBsAg of the occult HBV strain.
Result: Of note, A168V and T127P were detected in the HBsAg of the occult HBV strain (HB51).
Result: Seven amino acid substitutions were detected in HBsAg of strains isolated from pregnant women, including the conversion of Ile Leu at amino acid 110 (I110L), Thr Pro at amino acid 127 (T127P), Asp Glu at amino acid 144 (D144E), Ser Ala at a


  Case Report: Application of hepatitis B virus (HBV) deep sequencing to distinguish between acute and chronic infection.
 PMID: 33458253       2020       Wellcome open research
Conclusion: Mutations at amino acid level were also seen in surface antigen (V190A and T127P), both of which have been associated with CHB-AR in the context of immunosuppression ( Table 1).
Table: T127P


  [HBV pol/S gene mutations in chronic hepatitis B patients receiving nucleoside/nucleotide analogues treatment].
 PMID: 31130119       2019       Mikrobiyoloji bulteni
Abstract: Because of the HBV pol/S gene overlapping, in 27 patients immun-selected amino acid substitutions (sI110L, sT127P, sS114A, sT123A), in nine patients HBIg selected escape mutants (sP120R, sT123N, sE164D, sY134F, sQ129H, sT118A,


  Evolution of the serologic and virologic course of occult HBV infection in therapy experienced HIV co-infected patients.
 PMID: 28971485       2018       Journal of medical virology
Abstract: While the HBsAg gene sequences isolated from chronic HBV infection were genetically stable over time, OBI-associated variants (sP111R, sT127P, sY161F) were neither stable nor predominant during the course of infection.


  Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
 PMID: 29408943       2018       PloS one
Table: T127P


  Hepatitis B reactivation characterized by HBsAg negativity and anti-HbsAg antibodies persistence in haematopoietic stem cell transplanted patient after lamivudine withdrawal.
 PMID: 28806922       2017       BMC infectious diseases
Abstract: The genotypic analysis of the HBV strain identified T127P, F170FL and S204R mutations of HbsAg, which can hinder HBsAg recognition in a diagnostic assay.
Conclusion: The test did not reveal the presence of LMV resistance mutations but showed the presence of three mutations in HbsAg: T127P, F170FL and S204R.


  YMDD Motif Mutation Profile Among Patients Receiving Liver Transplant Due to Hepatitis B Virus Infection With Long Term Lamivudine/Immunoglobulin Therapy.
 PMID: 26300928       2015       Hepatitis monthly
Table: T127P


  Molecular Characterization of Pre-Core/Core and S Region of Hepatitis B Virus in Hemodialysis Patients With Occult Hepatitis B Infection.
 PMID: 26587212       2015       Jundishapur journal of microbiology
Abstract: There were three amino acid substitutions in the S region (T127P, P153L, and F170S) and one substitution in the RT region (Y135S).
Result: In this study, we observed a substitution in the RT region (Y135S) and three amino-acid substitutions in the S region (
Figure: B: arrows indicate mutations in the S region in positions T127P, P153L, and F170S.


  Mutation profiling of the hepatitis B virus strains circulating in North Indian population.
 PMID: 24637457       2014       PloS one
Result: Interesting to note that T127P surface peptide mutation was documented in 54.5% of the Genotype D isolates in comparison to 6.1% of Genotype A.
Table: T127P



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