HBV mutation literature information.


  [Influence of the mutants of hepatitis B surface antigen on the cell immunity].
 PMID: 16027776       2005       Zhonghua shi yan he lin chuang bing du xue za zhi
Abstract: But it should not be ignored that HBV T126S or M133T mutation may assert a potential impact on the cell immunity.
Abstract: It was deserved to point out that the HBsAg with T126S mutation could increase the expression of IFN-gamma in the culture medium while the HBsAg with M133T mutation induced more expression of IL-10.


  Prevalence of vaccine-induced escape mutants of hepatitis B virus in the adult population in China: a prospective study in 176 restaurant employees.
 PMID: 11851835       2001       Journal of gastroenterology and hepatology
Abstract: Four out of these six cases had a point mutation within the 'a' determinant; they were Gly-145-Ala, and Ile/Thr-126-Asn/Ser.


  Detection of hepatitis B virus surface antigen mutants in paraffin-embedded hepatocellular carcinoma tissues.
 PMID: 10949955       2000       Virus genes
1Abstract: Mutations on the ""a"" determinant (Thr126Ser, Gly145Arg, a double mutant Thr126Ser/Gln129Asn, Met 133Leu and Thr140Ile) were identified in 5 samples while the wild type sequence was found in 2 others."



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