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 HBV mutation literature information.


  Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia.
 PMID: 20595500       2010       The American journal of tropical medicine and hygiene
Abstract: A single amino substitution (T126I) in the S region was frequently found.


  "Molecular analysis of hepatitis B virus ""a"" determinant in asymptomatic and symptomatic Mexican carriers."
 PMID: 17217533       2007       Virology journal
Abstract: Mutations identified were Y100N, T126I, Q129H and N146K in the asymptomatic group, and F93I and A128V in the symptomatic group.
Result: Mutations identified in HBV strains from the asymptomatic group were Y100N, T126I, Q129H and N146K; whereas in strains from the symptomatic group identified mutations were F93I and A128V.
Table: T126I


  A unique amino acid substitution, T126I, in human genotype C of hepatitis B virus S gene and its possible influence on antigenic structural change.
 PMID: 16963200       2006       Gene
Abstract: The results showed that an amino acid substitution within the 'a' determinant, T126I, was unique to genotype C, may affect the antigenicity of the HBsAg, and may result in poorer clinical outcomes of patients infected with genotype C viral strains.



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