literature

HBV mutation literature information.

Broad Range of Hepatitis B Virus (HBV) Patterns, Dual Circulation of Quasi-Subgenotype A3 and HBV/E and Heterogeneous HBV Mutations in HIV-Positive Patients in Gabon.

PMID: 26764909 2016 PloS one

Table: T126I

Molecular epidemiology of hepatitis B virus isolated from Bangladesh.

PMID: 27652086 2016 SpringerPlus

Abstract: A significant number of mutations (Thr118Val, Thr

Result: Several mutations were observed in 'a' determinant region of S gene such as, T118V, T125M, T126I, P127T, A128V and T/S143L/M according to different genotypes of HBV (Table 1).

Table: Thr126Ile

Virological Characteristics of Acute Hepatitis B in Eastern India: Critical Differences with Chronic Infection.

PMID: 26571502 2015 PloS one

Result: Important mutations in the MHL of the surface gene that were detectable in acute hepatitis, were T125M (2.5%), T126I (10%), and Y134F (35%).

[Analysis on genotype distribution and mutation of major hydroponic region of hepatitis B virus in Liaoning].

PMID: 25907725 2015 Zhonghua liu xing bing xue za zhi

Abstract: The mutation rate of T126I was highest (8.64%).

Seroepidemiology and occult hepatitis B virus infection in young adults in Banjarmasin, Indonesia.

PMID: 25521058 2015 Journal of medical virology

Abstract: Thirteen amino acid substitutions were identified: T126S, P127S, Q129R, T131N, M133T, and Y161S in the HBsAg-positive group; P120T, T126I, G145S, Y161F, E164V, and V168F in the occult-HBV group; and T143S in both groups.

[Clinical significance of hepatitis B virus S gene mutation for recurrence of hepatitis B after liver transplantation].

PMID: 25243957 2014 Zhonghua gan zang bing za zhi

Abstract: One of the patients had T126I and G145A mutations, and the other had a M 133L mutation.

Genetic characterization and genotyping of hepatitis B virus (HBV) isolates from donors with an occult HBV infection.

PMID: 25040474 2014 Vox sanguinis

Abstract: Mutations in the S region (100%) were found especially in loop 1 of the major hydrophilic loop (MHL) at positions I110L, T114S, T126I and S113T, whereas mutations in the C region (65%) were within the basal core promoter region (position A1762T/G1764A) and precore region (position G1896A).

Molecular epidemiology and genotyping of hepatitis B virus of HBsAg-positive patients in Oman.

PMID: 24835494 2014 PloS one

Table: T126I/S

Naturally occurring hepatitis B virus B-cell and T-cell epitope mutants in hepatitis B vaccinated children.

PMID: 24379746 2013 TheScientificWorldJournal

5Result: Within the ""a"" determinant, one (N131T) substitution was detected in all isolates and three additional variants (T126I, T143S, and G145A) were found in subject Y5 (Table 3)."

8Discussion: We did not find the most important and best-documented G145R mutation, but we found a G145A mutation and other substitutions (T126I, N131T, and T143S) within the ""a"" determinant."

Epidemiology of HBV S-gene mutants in the Liguria Region, Italy: Implications for surveillance and detection of new escape variants.

PMID: 23296324 2013 Human vaccines & immunotherapeutics

Abstract: HBsAg resulted undetectable by 3 of the 8 samples, derived from patients with multiple mutations: T126I-T131A-C139Y-E/D144G, T126I-M133L, and P120Q-T126I.

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