literature

HBV mutation literature information.

Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt.

PMID: 26420301 2015 Virology journal

Abstract: Different amino acid substitutions were identified in overt infection group: S143L/T (16.2 %, 12/74) and P120T/S (2.7 %, 2/74).

Result: The most prevalent variant was S143L/T detected in 12 (16.2 %) of sequences, followed by T115S in 7 (9.5 %), Q129R in 5 (5.8 %), P120T/S in 2 (2.7 %), and K141R in one (1.4 %).

Result: The most prevalent variant was S143L/T detected in 16.2 % of sequences, followed by T115S in 9.5 %, Q129R in 5.8 %, P120T/S in 2.7 %, and K141R in 1.4 %.

Table:

PMID: 26457811 2015 PloS one

Result: There are twenty-one amino acid substitutions in the overlapping polymerase in all clones from father's sample, including F46S, R51K, H55Q, H55R, S57F, P109S, N118T, N124R, Y124H, Q125R, H126Q, 127R, N134D, C136R, N139K, Y141F, S143T, H160R, A211T, S213T and Q215H

HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study.

PMID: 24700252 2014 Infection

Abstract: Known mutants Y100C, P127T and P120A associated to Y134H and S143T and new S mutants, which may potentially affect HBsAg expression and secretion and anti-HBs binding, were detected in baseline sera persisting up to the end of 9 years follow-up.

Subgenotypes and mutations in the s and polymerase genes of hepatitis B virus carriers in the West Bank, palestine.

PMID: 25503289 2014 PloS one

Table: S143T

Discussion: It is probably that an unrecognized antibody response of the patients against their own HBsAg had exerted some selective pressure in favor of classical escape mutants and mutations to an amino acid associated with another genotype like Y134F and S143T.

[HBV vaccine escape mutations in a chronic hepatitis B patient treated with nucleos(t)ide analogues].

PMID: 23971933 2013 Mikrobiyoloji bulteni

Abstract: However, multiple HBV vaccine-escape mutations (sS143T + sD144E + sG145R + sE164D + sI195M) have been determined on the HBV overlapping pol/S gene region.

[A study on mutations of the overlapping hepatitis B virus surface and polymerase gene in patients with HBV reinfection after liver transplantations].

PMID: 18423147 2008 Zhonghua gan zang bing za zhi

Abstract: Mutations were detected as I126S, T131N, S143T and G145R in 'a' determinant and L110F, I113S, T160K in up- or down-stream of 'a' determinant.

Browser Board

Co-occurred Entities

Filtrator