literature

HBV mutation literature information.

[Identification by enzyme immunoassay of escape mutants S143L and G145R of hepatitis B virus (Hepadnaviridae: Orthohepadnavirus: Hepatitis B virus)].

PMID: 35293188 2022 Voprosy virusologii

Abstract: The kit specifically recognized the S143L substitution in contrast to the S143T variant.

Reactivation of Occult Hepatitis B Virus Infection During Long-Term Entecavir Antiviral Therapy.

PMID: 35359734 2022 Frontiers in microbiology

Abstract: Genetic sequencing of HBV showed the mutants of S143T, D144G, and G145R in the S gene region, and the mutant of site 1896 in the pre-Core region coexisted with the w

Result: Mutation analysis of this patient's HBV showed there were three mutants (S143T, D144G, and G145R) in the S gene region, and the mutant of site 1896 in the pre-Core region coexisted with the wild type (G1896A/G), but no mutation in the pre-S1, pre-S2, and BCP gene regions (Details shown in Table 3).

Evaluation of the pol/S Gene Overlapping Mutations in Chronic Hepatitis B Patients in Northern Cyprus.

PMID: 31880877 2019 Polish journal of microbiology

Table: S143T

Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence.

PMID: 29315352 2018 PloS one

Result: However, 60% of our strains had the S143T polymorphic mutation followed by G145K and K141R (for 2 patients) and M133I and D144N (for one patient) (Fig 4, Table 4).

Table: S143T

Discussion: The mutation S143T in our results was common to all HBV-A genotype strains.

Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.

PMID: 29408943 2018 PloS one

Table: S143T

HBV genotypes and drug resistance mutations in antiretroviral treatment-naive and treatment-experienced HBV-HIV-coinfected patients.

PMID: 27167598 2017 Antiviral therapy

Method: The sequences were examined for known vaccine escape mutations (sG145R/A, sP142S, sI/T126A/N/I/S, sQ129H/R, sM133L, sD144A/E, sP120S/E, sK141E, sP134I, and sT116N), immunoprophylaxis escape mutations (

Naturally Occurring Surface Antigen Variants of Hepatitis B Virus in Tunisian Patients.

PMID: 27544241 2016 Intervirology

Abstract: The global prevalence of the major hydrophilic region variants was 12.1%, with substitution S143L/T as the most frequent (4%).

Serologic and genotypic characterization of hepatitis B virus in HIV-1 infected patients from South West and Littoral Regions of Cameroon.

PMID: 27769271 2016 Virology journal

Result: The most prevalent mutations observed were found either in the 'a' region (L127P, S140T and S143T) or the B cell epitope and its surrounding region (G159A, F161Y and A168V).

Table: S143T

Genotyping and Mutation Pattern in the Overlapping MHR Region of HBV Isolates in Southern Khorasan, Eastern Iran.

PMID: 27882062 2016 Hepatitis monthly

Discussion: Sayan reported multiple HBV vaccine-escape mutations (S143T, D144E, G145R, E164D, I195M), of which 3 of them (D144E, S143L and E164D, one case for each) were seen in the current study.

Hepatitis B e antigen and hepatitis B surface antigen seroclearance with the emergence of lamivudine-associated and core mutations following CD4 elevation in a patient with hepatitis B and HIV.

PMID: 25786446 2015 Internal medicine (Tokyo, Japan)

Abstract: A full-length HBV DNA analysis indicated that HBsAg had been lost after the development of the rtS143T mutation, which corresponded to the emergence of the sF134L and core mutations.

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