HBV mutation literature information.


  Naturally occurring MHR variants in Turkish patients infected with hepatitis B virus.
 PMID: 18205223       2008       Journal of medical virology
1Abstract: When samples with ""a"" variants were evaluated by two different commercial HBsAg tests, only the isolate with Ser143Leu variation had a decreased reactivity in the assay using monoclonal antibodies for capture and detection."


  [Algorithm of serologic screening and assessment of prevalence of serologically meaningful mutations of HBsAg in hepatitis B virus carriers].
 PMID: 18283732       2007       Zhurnal mikrobiologii, epidemiologii i immunobiologii
Abstract: Analysis of primary nucleotide sequence revealed serologically meaningful mutations in S-gene of HBV in all 9 isolates: 3 of them contained substitution mutation G145R, 5--S143L, and one--T143M.
Abstract: Prevalence of HBsAg mutations in HBV carriers with high level of HBsAg was assessed for the first time: prevalence of G145R, S143L/T143M mutations, and all serologically atypical variants was 0.12%, 0.24%, and 0.76% respectively.


  A new hepatitis B virus vaccine escape mutation in a renal transplant recipient.
 PMID: 17210268       2007       Journal of clinical virology
1Abstract: The sequencing data showed that the HBV strain carried five amino acid substitutions in the major hydrophilic region of the S protein, one (sS143L) located at the ""a"" determinant."


  Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India.
 PMID: 16428891       2006       Intervirology
Abstract: Following lamivudine therapy, 14 of 57 (24.5%) patients developed 16 types of S-gene mutations (sP120S, sA128V, sS143L, sW182St., sT189I, sV190A, sS193L, sI195M, sW196L, sW196St., sS207R,


  Localization of hepatitis B surface antigen epitopes present on variants and specifically recognised by anti-hepatitis B surface antigen monoclonal antibodies.
 PMID: 11536229       2001       Journal of medical virology
Abstract: Whereas 6H6B6 did not detect mutations T123N, S143L, D144A and G145R, 27E7F10 binding was affected by mutations P120T and G145R.



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