Abstract: Most OBI strains were wild-type HBV, but some substitutions V168A, S174 N, V177A, Q129R/L/H, G145A/R in S region of genotype B (OBIB) and T47K/V/A, P49H/L, Q101R/H/K, S174 N, L175S, V177A, T118 M/R/K, G145R/A/K/E, R160K/N in S region of genotype C (OBIC) strains were identified in high frequency.
T
Characterization of the occult hepatitis B virus variants circulating among the blood donors from eastern India.
Result: In one case, A159G and R160K amino acid changes were found, and in the other, I68T amino acid substitution was observed.
Discussion: Interestingly, in one isolate, a quasispecies clone showed R160K substitution that resulted in serotype conversion, and thus, a unique mixed serotype pattern of infection was documented.
"Molecular analysis of hepatitis B virus ""a"" determinant in asymptomatic and symptomatic Mexican carriers."
Result: T113S, S114T, R122K, I126T and P127L were the most frequent in both asymptomatic and symptomatic patients; whereas A159G, R160K, F161Y and V168A were more frequent in symptomatic patients.
HBV mutation literature information.
PMID: 
2022
PloS one
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