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 HBV mutation literature information.


  Comparing the immunogenicity of hepatitis B virus S gene variants by DNA immunization.
 PMID: 11792065       2001       Viral immunology
Abstract: Computer modeling showed that a change from glutamine to leucine at 129 residue led to higher hydrophobicity and could result in decreased immunogenicity.


  A novel hepatitis B virus variant S 129 (Gln-->Leu): lack of correlation between antigenicity and immunogenicity.
 PMID: 10534722       1999       Journal of medical virology
Abstract: This A-to-T point mutation at nucleotide 540 resulted in a glutamine-to-leucine substitution at amino acid residue 129 (129L).



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