literature

Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.

PMID: 19301976 2009 The Journal of infectious diseases

Method: Mutations at 10 S envelope protein positions were considered possible vaccine-escape mutations, including sP120T, sI/T126N/A, sQ129H, sM133L, sK141E, sP142S, sD144A, sG145R, sF158Y, and s

PMID: 18649345 2008 Journal of medical virology

1Abstract: The K141E variant found in previous work was not detected and little variation was observed in the immunodominant ""a"" determinant; a single change was found in one vaccinated patient (Q129H) and nine changes detected among six unvaccinated carriers."

"Molecular analysis of hepatitis B virus ""a"" determinant in asymptomatic and symptomatic Mexican carriers."

PMID: 17217533 2007 Virology journal

Abstract: Mutations identified were Y100N, T126I, Q129H and N146K in the asymptomatic group, and F93I and A128V in the symptomatic group.

Result: Mutations identified in HBV strains from the asymptomatic group were Y100N, T126I, Q129H and N146K; whereas in strains from the symptomatic group identified mutations were F93I and A128V.

Table: Q129H

Frequency of hepatitis B virus 'a' determinant variants in unselected Spanish chronic carriers.

PMID: 16299725 2006 Journal of medical virology

Abstract: Met133Thr (2.2%); Gln129His, Met133Ile, Phe/Tyr134Asn (1.8%); Phe/Tyr134Leu, Gly145Ala (1.5%), and Pro120Thr (1.1%) were the most frequent.