Abstract: The
pre-S1,
pre-S2 and
S region sequences in
HCC tissue showed amino acid (AA) substitutions (
F19L,
P24L,
S59F,
T131I,
Q129H) and deletions (in positions 4,8, 17 and 86) in the
S region, AA substitutions (
T40S,
P124K,
L54P,
G76A,
N222T and
I273L) in
pre-S1 region and AA substitutions in
pre-S2 region (
P41H