HBV mutation literature information.


  [Study of the quasispecies dynamics of serum hepatitis B virus in a patient with acute exacerbations of chronic hepatitis B].
 PMID: 16420761       2006       Zhonghua gan zang bing za zhi
Abstract: All dominant quasispecies, except the one during the second resolution, carried core P5T, L60V, S155T, and precore G1896A mutations.


  Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure.
 PMID: 12727536       2003       Journal of clinical virology
Abstract: Subsequent to the instigation of antiviral therapy, the dominant drug resistant HBV which caused virological breakthrough and was associated with hepatic failure displayed a series of unique mutations particularly in the BCP (A1762T and G1764A) and in the polymerase (rtL180M, rtM204V, rtA222T and rtL336V), core (cP5T, cS26A,


  Coexistence of two distinct secretion mutations (P5T and I97L) in hepatitis B virus core produces a wild-type pattern of secretion.
 PMID: 12805468       2003       Journal of virology
Abstract: Core mutations P5T and I97L were found to be mutually compensatory in offsetting their respective distinct effects on virion secretion.



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