HBV mutation literature information.


  HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study.
 PMID: 24700252       2014       Infection
Abstract: Known mutants Y100C, P127T and P120A associated to Y134H and S143T and new S mutants, which may potentially affect HBsAg expression and secretion and anti-HBs binding, were detected in baseline sera persisting up to the end of 9 years follow-up.


  Mutation profiling of the hepatitis B virus strains circulating in North Indian population.
 PMID: 24637457       2014       PloS one
Discussion: All the 5 patients with Anti HBc positive (Occult Hepatitis) profile were found to contain mutations in this region (P127T).


  Hepatitis B virus gene mutations in liver diseases: a report from New Delhi.
 PMID: 22720023       2012       PloS one
5Result: Some substitutions such as P127T, V128A and D144N were observed in the immunologic domain of the ""a determinant"" region."


  Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment.
 PMID: 21671883       2011       Current HIV research
Abstract: Moreover, several mutations (sP105A, sI110S/L, sS136Y and sP127T/L) with significant differences in the frequency were identified in the S region of both cohorts.


  Monitoring of hepatitis B virus surface antigen escape mutations and concomitantly nucleos(t)ide analog resistance mutations in Turkish patients with chronic hepatitis B.
 PMID: 20382061       2010       International journal of infectious diseases
Abstract: In the NUC therapy group the prevalence was 8.5% (12/142), with the following patterns: sY100C+sI110V, sL109I, sP120T, sP127T, sG130R+sG145X, sS132A+sY134N, sY134N+sG145R, s


  [Analysis on mutation of S gene and P gene of hepatitis B virus in two counties of Sichuan Province].
 PMID: 20077675       2009       Zhongguo yi miao he mian yi
Abstract: RESULTS: Of 47 serum samples from patients with chronic HBV infection, amino acid mutation in 'a' determinant occurred in 12 samples (25.53%,12/47), correlating with T126A, I126T/S, P127T, T131N, M133L, M133T and T140I; high proportion of mutation clustered in first loop of 'a' determinant (92.86%,13/14), rtV207I mutation in C domain of reverse transcription occured in one sample.


  Analysis of hepatitis B surface antigen mutations in Mongolia: molecular epidemiology and implications for mass vaccination.
 PMID: 17115304       2007       Archives of virology
Abstract: Pro127Thr and Thr118Ala were the most common substitutions, which occurred in 6 (10.5%) and 3 (5.3%) subjects, respectively; none had Gly145Arg.



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