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 HBV mutation literature information.


  Clinical, virologic and phylogenetic features of hepatitis B infection in Iranian patients.
 PMID: 18803358       2008       World journal of gastroenterology
Abstract: In the HBV S region, the genetic variability was low, and the marked substitution was P120T/S, with a rate of 9.7% (n = 6).


  Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India.
 PMID: 16428891       2006       Intervirology
Abstract: Following lamivudine therapy, 14 of 57 (24.5%) patients developed 16 types of S-gene mutations (sP120S, sA128V, sS143L, sW182St., sT189I, sV190A, sS193L, sI195M, sW196L, sW196St., sS207R,


  Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.
 PMID: 17030194       2006       Gastroenterology
Abstract: As viral load rose again, a single viral population was progressively selected, harboring the rtV173L+L180M+A181V+N236T and sP120S mutations.
Abstract: RESULTS: At baseline, all HBV genomes carried a wild-type (wt) RT gene but 22% harbored the sP120S and 55% the sC107stop mutations within the surface (S) gene associated with vaccine escape.


  Effectiveness of hepatitis B vaccination in babies born to hepatitis B surface antigen-positive mothers in Italy.
 PMID: 11509998       2001       The Journal of infectious diseases
Abstract: One carrier child had a double mutation, with substitution of proline-->serine at codons 120 (P120S) and 127 (P127S) within the a determinant of HBsAg.


  "Identification of hepatitis B surface antigen variants with alterations outside the ""a"" determinant in immunized Singapore infants."
 PMID: 9841851       1999       The Journal of infectious diseases
1Abstract: Decreased binding to ""a"" determinant-specific monoclonal antibody was observed for variants Pro120 to Ser120, Ala159 to Val159, and Phe183 to Cys183."
Abstract: These include Asn116 to Thr116, Val118 to Ala118, Pro120 to Ser120, Ala159 to Val159, Phe183 to Cys183, and Val184 to Ala184.



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