Abstract: Met133Thr (2.2%); Gln129His, Met133Ile, Phe/Tyr134Asn (1.8%); Phe/Tyr134Leu, Gly145Ala (1.5%), and Pro120Thr (1.1%) were the most frequent.
[Influence of the mutants of hepatitis B surface antigen on the cell immunity].
PMID: 16027776
2005
Zhonghua shi yan he lin chuang bing du xue za zhi
Abstract: But it should not be ignored that HBV T126S or M133T mutation may assert a potential impact on the cell immunity.
Abstract: It was deserved to point out that the HBsAg with T126S mutation could increase the expression of IFN-gamma in the culture medium while the HBsAg with M133T mutation induced more expression of IL-10.
Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy.
PMID: 15953865
2005
Journal of Korean medical science
Abstract: Sequencing of the 'a' determinant revealed amino acid substitutions as I126S, T131N, M133T, and S136Y.
Result: These changes were consistent with amino acid substitutions at position I126S, T131N, M133T, and S136Y.
Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene.
Abstract: The three point mutations generate M133T, G119E, and R169P substitutions in the S domains of viral envelope proteins, respectively, without modifying the coding capacity of the overlapping polymerase gene.
Efficacy of combined lamivudine and adefovir dipivoxil treatment for severe HBV graft reinfection after living donor liver transplantation.
Abstract: Hepatitis B virus sequence analysis revealed several mutations in the polymerase gene (L528M, M552I, M552V) as well as in the surface gene region encoding the immunogenic major hydrophilic loop of the small surface protein (G130N, M133T, D144G).
Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers.
1Abstract: These changes involved 11 positions inside and 5 outside of the historical first and second loops of the ""a"" determinant, and included the following: Q101K, T115A, K122N, T123A, T126N, Q129N, G130R, T131I, M133T, F134L, C138Y, K141E, P142S, G145R, N146S, and C147F/R."
Amino acid substitutions Q129N and T131N/M133T in hepatitis B surface antigen (HBsAg) interfere with the immunogenicity of the corresponding HBsAg or viral replication ability.
1Abstract: Subsequent analysis of the predominant HBV strain revealed mutations in the ""a"" determinant: Met 133 Thr (codon change ATG to ACG) and Asn 131 Thr."
HBV mutation literature information.
PMID: 
2006
Journal of medical virology
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