Result: The point-mutations on the S gene that owned the rates of >30% of the population were: S53L (37.7%), A184V/G (39.3%), and S210K/N/R/S (39.3%); from 15 to <30% were L21S (29.1%),
Discussion: We found mutations as Y100C/F, P120S/T, R122K, I126T/N/S, S132P, M133T/S/L/I, G145R (the vaccine escape mutant, 2%), Y200F/W and Y206H/F/C as same as that were reported from other studies (Hudu et al.
Dried blood spot sampling for hepatitis B virus quantification, sequencing and mutation detection.
Discussion: All sequences obtained in this study were classified as HBV genotype E, which is known to show a clear genotypic divergence from all genotypes within the a determinant, where escape mutations can occur, reported that the types of polymorphisms at positions associated with escape mutations observed in HBV vary from one genotype to another and that the most common of these polymorphisms found in genotype E are T116N, P120L/S, Q129H/R, M133I, D144E, and G145I.
Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations.
Result: M133I/L/T and Result: Other VEMs that had an overall prevalence of >1% were T118A/R/V, M133I/L/T, A128V, Q129H/N/R, G145A/R, P120S/T and S/T143L/M (Figure 2A).
Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.
PMID: 32994690
2020
World journal of gastroenterology
Abstract: In particular, these mutations were sQ101H/K/R, sS114A/L/T, sT118A/K/M/R/S/V, sP120A/L/Q/S/T, sT/I126A/N/P/S, sM133I/L/T, sC137W/Y, sG145A/R, and sA159G/V.
Result: These mutations were PMID: 33458253
2020
Wellcome open research
Table: M133I
Molecular Epidemiology of Hepatitis B Virus in Turkish Cypriot.
PMID: 31880889
2019
Polish journal of microbiology
Table: M133I
Discussion: sQ129H, sM133I, and sY134N mutations are associated with occult infection with D genotype; also they impair S protein secretion.
Viral quasispecies of hepatitis B virus in patients with YMDD mutation and lamivudine resistance may not predict the efficacy of lamivudine/adefovir rescue therapy.
PMID: 30906435
2019
Experimental and therapeutic medicine
Result: In the present study, the most prevalent mutations were those in the S region (sP120Q, sQ129R, sT131I, sM133I, sG145R, sY161F/H, sI195M/T, sW196S/L, sW199C/L and sM213I/T; Table III).
Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence.
Result: However, 60% of our strains had the S143T polymorphic mutation followed by G145K and K141R (for 2 patients) and M133I and D144N (for one patient) (Fig 4, Table 4).
Table: M133I
Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
HBV mutation literature information.
PMID: 
2022
PloS one
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