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 HBV mutation literature information.


  Pro-oncogenic, intra host viral quasispecies in Diffuse large B cell lymphoma patients with occult Hepatitis B Virus infection.
 PMID: 31601912       2019       Scientific reports
Table: Met130Lys


  Virological Characteristics of Acute Hepatitis B in Eastern India: Critical Differences with Chronic Infection.
 PMID: 26571502       2015       PloS one
Result: No such changes were found in the X gene except at positions overlapping with the BCP (amino acid substitutions T127I, M130K and I131V).


  HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers.
 PMID: 16080797       2005       Virology journal
Abstract: A change in the amino acid sequences at positions 130 and 131 in the HBV-X protein (M130K and V131I) produced by T-A point mutations at the nucleic acids level has been associated with severe liver damage and HCC in patients from China and Africa.
Result: In this study, V131I also occurred alone in 5 samples (17%) of the 29 chronic patients; this event has been commonly reported by others; nevertheless M130K alone is very unusual.
Result: Table 1 shows the mutation rate of T-A in HBx for M130K and V131I amongst the three study groups.



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