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 HBV mutation literature information.


  Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.
 PMID: 35390033       2022       PloS one
Table: L98V


  Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
 PMID: 30584239       2018       Scientific reports
Abstract: Furthermore, reactivated HBV in 11 of 16 (69%) non-HSCT cases possessed substitutions associated with impaired virion secretion, including E2G, L77R, L98V, T118K, and Q129H in the S
Result: Amino acid substitutions of sE2G (n = 3), sL77R (n = 1), and sL98V (n = 1) in the small S protein that were associated with impaired virion secretion were also the predominant clone in patients in the non-HSCT group.


  Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.
 PMID: 27650283       2017       Journal of hepatology
Abstract: Some mutations (e.g., sE2G, sL21S, sR24K, sT47A/K, sC69stop (sC69*), sL95W, sL98V, and sG145R) negatively correlated with serum HBsAg levels.
Discussion: We identified several new HBV mutations (sE2G, s PMID: 28939157       2017       Vaccine
Abstract: Four sites (A5T/S, L21S, T/A126S and T/N131I/A) and 13 sites (N3S, T5A, G10Q/R/E, L21S, T47K/A/V, L9
Abstract: More importantly, N3S, L21S, T47K, L98V, I/S126T and L213I mutations were detected in 1 (2.5%), 1 (2.5%), 1 (2.5%), 3 (7.5%), 1 (2.5%), 1 (2.5%) genotype C HBV infected Chinese younger with neonatal HBV vaccination, respectively.


  Characterization of the occult hepatitis B virus variants circulating among the blood donors from eastern India.
 PMID: 24302857       2013       TheScientificWorldJournal
Result: At least 4 different genotype/subgenotype unrelated aa mutations are observed: V96A (1/47; 2.13%), L98V (1/47; 2.13%), Y100C (1/47; 2.13%), and I1110L (3/47; 6.38%) (data not shown).


  Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
 PMID: 20119580       2010       Journal of Korean medical science
Result: Similarly, in Group P, there was one case of each of the following mutations: F41C, A45V, P49L, Q54L, P62L, I92T, L98V, T140S, A157V, W182stop, and S204R.


  Comparison of the technical and clinical performance of the Elecsys HBsAg II assay with the Architect, AxSym, and Advia Centaur HBsAg screening assays.
 PMID: 20336717       2010       Journal of medical virology
Abstract: However, the Elecsys HBsAg II assay recognized a native mutant sample (L94S, L97V, L98V, T123A) that the Architect HBsAg assay failed to detect.



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